The editor of the Lancet has already complained that “half” of published studies are simply false. Corruption of science is a major deal, and big business.
Here are some ideas to address it:
For example, in psychology, two-thirds of 100 high-profile papers could not be replicated. In preclinical studies (such as oncology drug targets), failure-to-replicate rates have varied from 75% to 89%. Candidate gene studies failed-to-replicate about 99% of the time when we moved to the genome-wide era with more rigorous methods.